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    • dosage mg 200 mg
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Description

Diflucan (fluconazole) is an antifungal medication used to treat candidiasis and other fungal infections, including:

  • Vaginal, oral, and urinary tract infections
  • Pneumonia, peritonitis, and systemic fungal infections
  • Cryptococcal meningitis (prevention & treatment)

Mechanism: Disrupts fungal cell membrane formation, killing sensitive fungi.

Dosage & Administration

Adults:

  • Vaginal yeast infection: 150 mg single dose
  • Oral/throat infections: 50 mg daily for 7-14 days
  • Skin infections: 50 mg daily for 2-4 weeks
  • Severe systemic infections: 400 mg on Day 1, then 200-400 mg daily for 6-8+ weeks
  • Prevention (immunocompromised): 50-400 mg daily

Children (4 weeks - 15 years):

  • Mucosal infections: 3 mg/kg once daily
  • Systemic infections: 6-12 mg/kg once daily
  • Prevention: 3-12 mg/kg daily

Infants (under 4 weeks):

  • Same doses as above, but given every 2-3 days

Note:

  • Take with or without food, preferably at the same time daily.
  • Use the provided measuring spoon for liquid form.
  • Improvement typically seen within 24 hours, but complete recovery may take days.

Precautions

  • Avoid if allergic to fluconazole or other azole antifungals (e.g., ketoconazole).
  • Use cautiously in liver/kidney disease (dose adjustments may be needed).
  • May cause dizziness—avoid driving or operating machinery.
  • Limit alcohol (increases liver stress).
  • Not recommended in pregnancy/breastfeeding without medical advice.

Contraindications

Do not use if you have:

  • Severe liver/kidney impairment
  • Heart rhythm disorders (QT prolongation risk)
  • Low calcium, magnesium, or potassium levels

Possible Side Effects

Common (usually mild):

  • Nausea, headache, dizziness
  • Diarrhea, stomach pain
  • Skin rash, itching

Serious (seek medical help):

  • Allergic reactions (swelling, difficulty breathing)
  • Liver problems (jaundice, dark urine, abdominal pain)
  • Severe skin reactions (blistering, peeling)
  • Irregular heartbeat, seizures

Drug Interactions

Diflucan affects many medications, including:

  • Blood thinners (warfarin) → Increased bleeding risk
  • Diabetes drugs (glyburide, glipizide) → Risk of low blood sugar
  • Seizure meds (phenytoin, valproic acid) → Altered levels
  • Immunosuppressants (cyclosporine, tacrolimus) → Toxicity risk
  • Sedatives (diazepam, midazolam) → Enhanced drowsiness

Consult your doctor before combining with other drugs.

Missed Dose & Overdose

  • Missed dose: Take as soon as remembered. Skip if close to the next dose.
  • Overdose symptoms: Confusion, hallucinations, irregular heartbeat → Seek emergency care.

Storage

  • Keep at 15-25°C (59-77°F) in a dry, dark place.
  • Keep away from children and pets.
  • Do not use past expiration date.

Note: Always follow your doctor's instructions for safe and effective treatment.

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