Albenza is a broad-spectrum anthelmintic effective against:
- Roundworms
- Tapeworms
- Flukes
Mechanism of Action
- Binds to parasite tubulin, disrupting microtubule formation
- Impairs glucose absorption in parasites
- Depletes glycogen stores and ATP production
- Leads to parasite immobilization and death
Administration Guidelines
- Take with meals (especially fatty foods) for better absorption
- Swallow tablets whole with water (may crush for children)
- Complete full course as prescribed
- Repeat dosing may be required for some infections
Important Precautions
- Contraindicated in pregnancy (avoid conception for 1 month post-treatment)
- Use caution with:
- Liver/biliary tract disease
- Bone marrow disorders
- Known benzimidazole hypersensitivity
- Limit alcohol consumption (increased hepatotoxicity risk)
Monitoring Requirements
- Liver function tests
- Complete blood counts
- Neurological assessment
Common Side Effects
- Gastrointestinal disturbances
- Headache/dizziness
- Transient hair loss
- Elevated liver enzymes
Serious Adverse Effects
- Hepatotoxicity (including liver failure)
- Bone marrow suppression
- Severe allergic reactions
- Neurological symptoms
Storage Instructions
- Keep at 20-25°C (68-77°F)
- Protect from moisture and light
- Store away from children/pets
Patient Counseling
- Report any persistent fever/sore throat
- Monitor for signs of liver problems
- Complete all prescribed doses
- Use reliable contraception during treatment
Note: Regular blood monitoring is essential during therapy. Discontinue immediately and seek medical attention for severe reactions.
