Alkeran is an alkylating agent used to treat multiple myeloma, ovarian cancer, and ocular melanoma that has metastasized to the liver. It may also be prescribed off-label for other cancers as determined by your oncologist.
Dosage & Administration
- Available as oral tablets.
- Follow your doctor's prescribed schedule strictly.
Precautions
- May cause dizziness or fatigue—avoid driving or operating machinery if affected.
- Not recommended during pregnancy or breastfeeding due to potential harm to the baby.
- Use with caution if you have liver/kidney disease or prior radiation therapy.
- Limit sun exposure and wear protective clothing to prevent skin reactions.
Contraindications
- Allergy to melphalan.
- Severely suppressed bone marrow function.
Possible Side Effects
- Nausea and vomiting.
- Diarrhea.
- Mouth sores.
- Loss of appetite.
- Fatigue and weakness.
- Reversible hair loss.
Drug Interactions
May interact with:
- Antibiotics (e.g., nalidixic acid).
- Immunosuppressants (e.g., cyclosporine).
- Antacids (e.g., cimetidine).
Missed Dose
- Take as soon as remembered unless close to the next dose.
- Do not double dose.
Overdose Symptoms
- Severe nausea, vomiting, diarrhea.
- Mouth ulcers.
- Dangerously low blood cell counts.
- Seek immediate medical help if suspected.
Storage
- Keep at 20°C–25°C (room temperature).
- Protect from moisture, heat, and sunlight.
- Store out of reach of children and pets.