Aldactone 25 mg 120 pills

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  • Manufacturer: RPG Life Sciences
  • SKU: 638469011144293456
  • Availability: In Stock
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  • Ingredient Spironolactone
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Description

Aldactone is a potassium-sparing diuretic and aldosterone antagonist used for:

  • Hypertension (combined therapy)
  • Edema in heart failure, cirrhosis, and nephrotic syndrome
  • Management of fluid retention

Mechanism of Action

  • Blocks aldosterone receptors in distal nephron
  • Promotes sodium excretion
  • Reduces potassium and magnesium loss
  • Modest diuretic effect develops over 2-5 days

Dosage Guidelines

  • Initial dose: 50-100 mg daily (1-2 divided doses)
  • Maximum dose: 200 mg daily
  • Take with meals (preferably at bedtime)
  • Minimum treatment duration: 2 weeks

Important Precautions

  • Monitor electrolytes (potassium/sodium) regularly
  • Avoid potassium-rich foods/supplements
  • Limit salt intake
  • Maintain proper hydration
  • Do not discontinue abruptly for hypertension

Contraindications

  • Hyperkalemia
  • Addison's disease
  • Severe renal/hepatic impairment
  • Concomitant potassium-sparing agents
  • Pregnancy

Potential Side Effects

  • Electrolyte imbalances
  • Gastrointestinal disturbances
  • Drowsiness/headache
  • Menstrual irregularities
  • Gynecomastia (dose-dependent)

Drug Interactions

  • Increases digoxin toxicity risk
  • Enhances effects of other potassium-elevating drugs
  • NSAIDs may reduce effectiveness

Missed Dose Management

  • Skip if close to next scheduled dose
  • Never double dose

Overdose Symptoms

  • Severe drowsiness
  • Confusion
  • Gastrointestinal distress
  • Skin rash

Storage Conditions

  • Room temperature (<25°C/77°F)
  • Protect from moisture

Special Notes

  • Therapeutic effects may take several weeks
  • Regular blood tests recommended
  • Report any muscle weakness or irregular heartbeat

Note: This medication requires careful medical supervision due to its impact on electrolyte balance.

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